If you’ve already read my post on ‘Iron, the Women’s Essential Nutrient’ and ‘Iron Pathology’  then this will start to make more sense if you have found yourself to be low in Iron and feel it’s your thyroid despite being told you are fine.

Iron is intricately involved with Thyroid hormones, in fact, dependant on the mineral, bottom line, low Iron, low Thyroid despite having a Thyroid condition. 

Having low Iron affects the production of the Thyroid hormone in several ways:

  1. In the Thyroid gland where T4 is made an enzyme called Thyroid Peroxidase enzyme (TPO) depends on Iron to work. So, if there is not enough Iron, the production of T4 will be reduced.  Now you are familiar with how easy it is to be low in Iron, it can make you wonder if your hypothyroid symptoms are not due to an iron deficiency.  This enzyme’s antibody, TPOab is tested for the diagnosis of Hashimotos.
  1. There are enzymes all through the body and brain called Diodinases, de-iodin-ase and they break an iodine molecule from T4 down and convert it into T3. These enzymes depend on Iron to be able to work. The ratio that we like this to happen is a 3:1, ie 3x T4 to 1x T3.  Having low iron may be one of the few reasons that there is poor conversion. 
  1. When the body detects there is low iron in the blood, it increases the amount of T4 that is changed into Reverse T3 (RT3) which is the opposite of active T3, this will slow you down and cause fatigue.
  1. Iron is an important part of the mechanism that transports thyroid hormone into cells and lack of it can lead to pooling of hormone. This can lead to being hypothyroid even though there are normal T3 levels and it produces a thyroxine resistance situation.

Because of the dependence of Iron for the conversion of T4 to T3, some symptoms may worsen if you are put on Thyroxine and the underlying Iron deficiency has not been addressed – that’s like revving the accelerator on the taxi when there is no gas.  Symptoms may be anxiety, palpitations, or irregular heartbeats.

Ironically being hypothyroid may in return cause a lack of Iron because when we are low in thyroid hormones we lack the ability to have good digestion, and tend to have low stomach acid or more susceptible to Immune diseases like being Celiac.

Dysphagia is a term that means difficulty in swallowing.  A frequent need to clear the throat, particularly when under stress, is a classic sign of possible low thyroid activity and low iron status.

Women who experience heavy menstruation can become iron-deplete and therefore create a hypothyroid state.

Ferritin deficiency is the primary cause of hair loss in premenopausal women, and it’s often why women with Hashimotos continue to lose hair despite normal thyroid levels.

As you have read, Iron is extremely important, so make it a priority to have your levels assessed on a regular basis.

If you’d like to know more about this or other topics, you are welcome to join my free membership on face book. Thyroid, Metabolic, Hormone Harmony Hub. 

I’d love to see you there

Inspiring Wellness



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